Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine cardiac side effects Plaquenil treatment for vasculitis What are some other side effects of Hydroxychloroquine? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away Dizziness. Headache. Feeling nervous and excitable. Does anyone take methotrexate and hydroxychloroquine and has anyone had problems with hydroxychloroquine. Too many side effects of both methotrexate and Hydrochloroquine prompted my beautiful daughter to encourage me to go on a strict diet with no meds. I did check with my gp and rheumy re this. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Methotrexate and hydroxychloroquine side effects Combination therapy with methotrexate and hydroxychloroquine for., Does anyone take methotrexate and hydroxychloroquine. Hydroxychloroquine binding action of mechanismIs plaquenil still available Description and Brand Names. Drug information provided by IBM Micromedex US Brand Name. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Hydroxychloroquine Oral Route Description and Brand.. Methotrexate Oral Route Side Effects - Mayo Clinic. Common and Rare Side Effects for Methotrexate Anti.. Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Combined use of methotrexate with gold, penicillamine, hydroxychloroquine, sulfasalazine, or cytotoxic agents, has not been studied and may increase the incidence of adverse effects. Rest and physiotherapy as indicated should be continued. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Are there any reasons I won't be prescribed hydroxychloroquine? Before starting on hydroxychloroquine your doctor may take a blood test to check that your liver and kidneys are working normally, but you won't need any regular blood tests during the treatment.