Weight based dosing plaquenil

Discussion in 'Hydroxychloroquine Sulfate' started by shram, 21-Feb-2020.

  1. AdmiralX3 User

    Weight based dosing plaquenil


    If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range (/= 6.5 mg/kg/day). This graph shows various formulas that have been proposed for deriving ideal body weight for women, because virtually all cases of hydroxychloroquine toxicity have been female.

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    The mean AUC of methotrexate was increased 52% and the mean Cmax was reduced 17% when a single dose of methotrexate was given with a dose of hydroxychloroquine 200 mg oral. Close monitoring for evidence of methotrexate toxicity should be done in patients receiving this combination, especially in those with reduced renal function. The study is based on hydroxychloroquine sulfate the active ingredients of Plaquenil and Plaquenil the brand name. Other drugs that have the same active ingredients e.g. generic drugs are not considered. Dosage of drugs is not considered in the study. Regarding the dosing of hydroxychloroquine, we advocate the use of a weight-based dosing regimen with a cap at 400 mg per day, except in the case of renal insufficiency, when the dose should be.

    For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. The usual hydroxychloroquine dose that is prescribed is 400 mg/day.

    Weight based dosing plaquenil

    Hydroxychloroquine Blood Levels in SLE Clarifying dosing., Will you have Weight increased with Plaquenil - eHealthMe

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  6. For children and infants, the dose is based on weight. Usually, 5 mg per kg of body weight about 2.3 mg per pound once weekly is recommended, not to exceed the normal adult dosage. Plaquenil comes only in adult-strength tablets, which taste extremely bitter when crushed or chewed.

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    Adults— Standard dosing At first, 800 milligrams mg 4 tablets taken as a single dose. Then, 400 mg taken 6 hours, 24 hours, and 48 hours after the first dose. Weight-based dosing Dose is based on body weight and must be determined by your doctor. At first, 13 milligram mg per kilogram. SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day. The usual hydroxychloroquine dose that is prescribed is 400 mg/day. For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. As one can see, the height that corresponds to an ideal body weight of 135 pounds varies across the formulas.

     
  7. Samohval New Member

    A 45-year-old black female presented with no ocular or visual complaints. However, her medical history was significant for a recent diagnosis of lupus. Humphrey Visual Field Findings in Hydroxychloroquine Toxicity Toxic Retinopathy With Hydroxychloroquine Therapy - JAMA Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
  8. Strem Moderator

    Plaquenil is the brand name for the prescription drug hydroxychloroquine. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Hydroxychloroquine Plaquenil Refusing to take Plaquenil - HealthBoards
     
  9. bekas1976 Guest

    Plaquenil and Sleep - Sjogren's World Hi Missy I don't have problems going to sleep with the plaquenil, but I do have increasngly bizarre dreams - not frightening, but very odd. I can cope with these though, because the plaquenil has been a Godsend.

    Hydroxychloroquine Sulfate Sleep Disorder Reports.
     
  10. vovakula Moderator

    Plaquenil Withdrawal – Life As An Anomaly Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me.

    Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus