Long-term progression of hydroxychloroquine retinopathy off the drug

Discussion in 'Hydroxychloroquine Sulfate' started by mrwert, 21-Feb-2020.

  1. vadbars Guest

    Long-term progression of hydroxychloroquine retinopathy off the drug


    Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.

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    The risk of toxic retinopathy in patients on long-term hydroxychloroquine therapy. JAMA Ophthalmol 2014;153–60. Wolfe F, Marmor MF Rates and predictors of hydroxychloroquine retinal toxicity in patients with rheumatoid arthritis and systemic lupus erythematosus. Baseline and periodic screening for retinopathy is necessary for rheumatologic uses and in long-term therapy eg, 1 to 5 years depending on patient risk factors AAO Marmor 2016; Travassos 2019. Tolerability GI upset nausea, vomiting, diarrhea is a common adverse effect. Dividing doses, taking with food, and, if appropriate, gradual dose escalation in treating rheumatologic diseases may improve tolerability Wallace 2019. Data are available on the presenting features and long-term follow -up of patients with hydro xychloroquine retinopathy, making it diffic ult to surmise the clinic al course of patients

    Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.

    Long-term progression of hydroxychloroquine retinopathy off the drug

    Expanded spectral domain-OCT findings in the early., Hydroxychloroquine Professional Patient Advice -

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  4. Hydroxychloroquine HCQ is toxic to the retina in proportion to daily dose and duration of use, causing a characteristic retinopathy in Caucasian patients with loss of photoreceptors and eventually RPE changes in a ring around the fovea. 1,2 The mechanism of this toxicity is unclear, as animal experiments have shown the drug can affect all retinal layers, 3 whereas the damage seen in clinical.

    • Localization of Damage in Progressive Hydroxychloroquine Retinopathy On..
    • Progression of Hydroxychloroquine Toxic Effects After Drug..
    • AMERICAN COLLEGE OF RHEUMATOLOGY.

    Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. May 16, 2011 Nevertheless, retinopathy begins to appear with long-term use, and retinopathy is serious insofar as there is no known treatment. It can progress for a year or more after stopping the drug and, if not recognized early at the point of screening, it can lead to functional blindness. Pham B, et al. Long-term progression of hydroxychloroquine retinopathy off the drug. Presented at Association for Research in Vision and Ophthalmology annual meeting; April 29-May 3, 2018; Honolulu.

     
  5. zanxus XenForo Moderator

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  6. Delico User

    Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Efficacy of 3 Regimens of Chloroquine and Primaquine for. Chloroquine & Hydroxychloroquine supporting chemo. Effects of chloroquine on viral infections an old drug.
     
  7. Boolkin Moderator

    CDC - Malaria - Diagnosis & Treatment United States. In addition, any of the regimens listed below for the treatment of chloroquine-resistant malaria may be used for the treatment of chloroquine-sensitive malaria. Prompt initiation of an effective regimen is vitally important and so using any one of the effective regimens that is readily at hand would be the preferred strategy.

    Chloroquine - Wikipedia