Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Lupus extreme anxiety plaquenil Hydroxychloroquine mechanism of action Can plaquenil cause problems with teeth and gums Feb 19, 2020 PLAQUENIL is indicated for the treatment of uncomplicated malaria due to P. falciparum, P. malariae, P. ovale, and P. vivax. PLAQUENIL is indicated for the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported. Limitations Of Use In Malaria. PLAQUENIL is not recommended for the treatment of complicated malaria. Oct 01, 2012 However, most reports have described chloroquine‐induced hyperpigmentation, and hyperpigmentation due to hydroxychloroquine has been rarely reported. We herein report a case of hydroxychloroquine‐induced hyperpigmentation. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine -sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Chloroquine hyperpigmentation Hydroxychloroquine-induced Hyperpigmentation of the Skin., Hydroxychloroquine‐induced hyperpigmentation, The Journal of. Chloroquine bafilomycin a1 conventional autophagyIncidence of retinal toxicity from plaquenilCan a pregnant woman take chloroquine Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Chloroquine Oral Uses, Side Effects, Interactions, Pictures.. Hydroxychloroquine - Wikipedia. Hydroxychloroquine-Associated Hyperpigmentation Mimicking.. Chloroquine diphosphate and hydroxychloroquine sul-fate, are administered for treatment of several dermato-logic and rheumatologic disorders, and they are known to cause hyperpigmentation of the oral mucosa 9,15. Systemic administration of these drugs for a prolonged period is responsible for the appearance of multifocal About 25% of patients receiving chloroquine or hydroxychloroquine for several years develop bluish-grey pigmentation on face, neck and sometimes lower legs and forearms; Continuous long-term use may lead to blue-black patches, especially in sun-exposed areas; Nail beds and corneal and retinal changes may also develop; Cytotoxic drugs The antimalarials most widely known to trigger dyschromia are chloroquine, hydroxychloroquine, amodiaquine, and quinacrine. Hyperpigmentation typically appears within 1-9 weeks following drug administration at doses as low as 15-30 mg and can be accompanied by pruritus, pigmented banding of the patient's nails, or both. pigmentation is.