The study is created by e Health Me from 81 Plaquenil users and is updated continuously. On e Health Me, you can evaluate side effects and drug interactions from 16 million FDA reports. Neurontin and plaquenil interactions Chloroquine metabolism Following a single 200 mg oral dose of PLAQUENIL to healthy males, the mean peak blood concentration of hydroxychloroquine was 129.6 ng/mL, reached in 3.26 hours with a half-life of 537 hours 22.4 days. 50.3 ng/mL reached in 3.74 hours with a half-life of 2963 hours 123.5 days. I take mine 200 mg two times a day. If the drug doesn't bother you, I think that is the most common. I have forgotten my morning dose and taken two pills later in the day together and I didn't have any problem. Children—Dose is based on body weight and must be determined by your doctor. At first, 13 mg per kg of body weight taken as a single dose. Then, 6.5 mg per kg of body weight taken 6 hours, 24 hours, and 48 hours after the first dose. However, dose is usually not more than 800 mg for the first dose and not more than 400 mg for the next doses. You can also discuss your drugs with qualified professionals to ensure drugs are working to improve your health. The study is based on hydroxychloroquine sulfate (the active ingredients of Plaquenil) and Plaquenil (the brand name). The results are personalized to your gender and age (0-99 ). Plaquenil dosage sjogren& 39 Ask the Expert Plaquenil and Sjögren’s, Plaquenil Dosage - Sjogren's World Plaquenil and diarrhea and weight lossMix with chloroquine for fishPlaquenil and juvenile arthritisChloroquine brazilPlaquenil and hair dye My rheumy has just prescribed Plaquenil for my SS. Reading the warnings, I see that there is concern about effects on the eyes retinas. I am very concerned about this and am wondering if anyone out there has been put on an alternative drug to treat their SS. I have several issues with my. Alternatives to Plaquenil DailyStrength. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. How effective is Plaquenil for Sjogren syndrome by duration.. Nov 25, 2019 Initial dose 400 mg 310 mg base orally 1 to 2 times a day; this dose may be continued for several weeks or months, depending on patient response. Maintenance dose 200 to 400 mg 155 to 310 mg base orally daily. Comments -Each dose should be taken with a meal or a glass of milk. Hydroxychloroquine is the immunomodulatory drug most frequently used for primary Sjögren syndrome, 7 usually prescribed for patients with fatigue, arthralgia, and myalgia 8-10 rather than severe systemic manifestations. The latter symptoms are treated with corticosteroids and azathioprine, cyclophosphamide, mycophenolate mofetil, or rituximab. Aug 29, 2014 Several risk factors may increase the likelihood of retinal toxicity from Plaquenil such as, age of greater than 60 years, daily dose more than 6.5 mg/kg; use of the drug more than 5 years, obesity, preexisting retinal disease and, renal or liver failure.