Its use is becoming increasingly popular for skin disease, arthritis, and other non-life-threatening forms of disease that have not responded to medications such as hydroxychloroquine or low doses of prednisone. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Hydroxychloroquine how do you take it Plaquenil and bypass surgery Dec 28, 2017 Plaquenil is a maintenance drug in order to help prevent organ damage. Methotrextate is usually given for RA. I was on both for 6 years. No issues except some minor stomach nausea and was given a med for that which helped. For Rheumatoid Arthritis Better than the biologics or methotrexate that caused my lungs to burn up. However, after 7 years of 200 mg b.i.d. I think the time has come to quit this too, I have been experiencing nausea and liver pain for the last few weeks and just recently vomiting and hives followed by four hours of dry heaves. Methotrexate is once a week usually and most of the side effects would hit the next day so some people choose to take it on a Friday or Saturday night and sleep through any potential side effects some people report that caffeine may lower the efficacy of methotrexate, though results have been inconclusive. If you think you may have a medical emergency, immediately call your doctor or dial 911. Never ignore professional medical advice in seeking treatment because of something you have read on the Web MD Site. Methotrexate vs plaquenil for lupus Methotrexate and its benefit for Sjögren’s patients, Hydroxychloroquine Compared to Alternatives - Chloroquine phosphate and leather coralsChloroquine dosing prophylaxisPlaquenil ear ringingDo i need to let pharmacy know labs ok plaquenil Do you think I should try the Plaquenil first before starting MTX or is it fine to jump to MTX? From what I read so far, seems like methotrexate is a bigger drug with more side effects so plaquenil would be the better choice. Any information would be helpful. Answer. Both drugs are well tolerated and useful in patients with lupus associated. MTX vs Plaquenil - Arthritis Information. Plaquenil vs Methotrexate rheumatoid - reddit. Mycophenolate Cellcept vs Methotrexate lupus. These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. Interaction between Methotrexate and Plaquenil There is no known interaction between Methotrexate and Plaquenil in our records. However, an interaction may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice. Methotrexate is an arthritis medication and a cancer medication. Plaquenil is an arthritis medication and an anti infectious agent. There may be a negative interaction between Methotrexate and alcohol. There may be a negative interaction between Plaquenil and alcohol.