Please review the following URL and make sure that it is spelled correctly. Atovaquone/Proguanil (Malarone) Adults: 1 adult tablet daily. Plaquenil and eyes Plaquenil menstruation disturbance According to the US CDC, chloroquine is considered the drug of choice for malaria prophylaxis during pregnancy for women traveling to areas where chloroquine-resistant Plasmodium falciparum has not been reported; for travel to areas where chloroquine resistance is present, this drug is the only medication recommended for malaria prophylaxis. Abstract. Childhood anaemia is a major public health problem in malaria holoendemic areas. We assessed the effects of antimalarial treatment in an area with drug-resistant falciparum malaria on haemoglobin levels in small children by applying the 1996 World Health Organization in vivo method for the evaluation of standard chloroquine treatment at the community level. Chloroquine is the drug of choice for the treatment of non-falciparum malaria but chloroquine-resistant P. vivax has been reported in the Indonesian archipelago, the Malay Peninsula, including Myanmar, and eastward to Southern Vietnam. This drug should be used during pregnancy only if clearly needed and the benefit outweighs the risk.-According to some authorities: Use is considered acceptable. Begin 1-2 days before travel, daily during travel, and for 7 days after leaving. Drug of choice for chloroquine resistant malaria in pregnancy Malaria – Knowledge for medical students and physicians, Chloroquine treatment for uncomplicated childhood malaria in an area. Plaquenil visual field 10-2 TRAVEL TO AREAS WITH CHLOROQUINE-RESISTANT MALARIA. Primaquine and tafenoquine should not be used during pregnancy because the drug may be passed transplacentally to a G6PD-deficient fetus and cause hemolytic anemia in utero. Not a good choice for last-minute travelers because drug needs to be started ≥2 weeks before travel. Malaria - Chapter 4 - 2020 Yellow Book Travelers' Health.. Malaria, treatment Treatment summary BNF content.. Which medications are used to treat malaria during pregnancy?. In areas with chloroquine-sensitive malaria. Chloroquine is the drug of choice for the treatment of chloroquine-sensitive falciparum malaria, chloroquine-sensitive P. vivax, as well as P. ovale, P. malariae and P. knowlesi infections Footnote 55. This agent is approved in the United States for the prophylaxis and treatment of mild chloroquine-resistant malaria. It may be a good prophylactic option for patients who are visiting areas with chloroquine-resistant malaria and who cannot tolerate mefloquine. Each tab combines 250 mg of atovaquone and 100 mg of proguanil hydrochloride. Specific antimalarial drugs • Quinine – Drug of choice for chloroquine-resistant malaria • Lumifantrine, Amodiaquine, Atovaquone – Reserve medication 30. Tuberculosis in pregnancy First-line drugs • Isoniazid • Rifampicin • Ethambutol • Pyrazinamide Contraindicated • Streptomycin 31.