It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Does hydroxychloroquine make you gain weight Plaquenil vision Chloroquine side effects depression I have had the same on my forearms but one spot disappeared after a year. I'm not sure how or why it did but I was glad, it just looked like a dark circle on my arm. I am not if my heritage has anything to do with it Native American, but the Plaquenil does make me extremely photosensitive. Of course it lightens some in the Winter months. Continue applying the dark spot removal home remedy for about two weeks so as to get the desired result. If you have a delicate skin, then you can dilute the lemon juice using some amount of plain water, rose water, or even some honey. You may also use lime juice to do away with black spots, using it in the same manner as indicated above. Hyperpigmentation, or “dark spots,” can be caused by acne scars, excessive sun exposure, or hormonal changes, according to David E. Bank, MD, of New York-Presbyterian Hospital. “There are a. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil and dark spots Plaquenil and skin discoloration - Sjogren's World, Dark Patches on Skin Folds, under Breasts, Itchy, Causes. Hydroxychloroquine sulfate tablets uses Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Long-Term Side Effects of Plaquenil for Rheumatoid.. How to Get Rid of Dark Spots on the Face. Brown spots/discoloration on your face. Lupus Forums at.. Acne After the pimple dries out, it could leave a dark brown spot in its place. In some cases, the hyperpigmented spot could also be purple or red in colour. This is called postinflammatory. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. What causes drug-induced skin pigmentation? Several mechanisms may be involved in the drug-induced changes of pigmentation of the skin. Certain heavy metals, such as iron, silver, and gold, may be deposited in the dermis following damage to dermal vessels. If deposited in sufficient quantities a distinctive change in skin colour may be seen without any significant increase in melanin.