Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. What are the most common side effects of plaquenil Can plaquenil cause lung problems Hydroxychloroquine treatment for lyme disease How common is chloroquine retinopathy Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Incidence not known Blistering, peeling, loosening of the skin And plaquenil does miracle for pain. Try to not remove it from your treatment plan. I had this med removed for 2 years and suffered quite a lot of joint, muscle and tendon pain. The main side effect from plaquenil is some digestive problems. Severe is retinal degradation, everyone should get an eyefield test yearly. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Bad side effects of plaquenil The Risk of Retinal Toxicity with Plaquenil, Plaquenil & Weight Gain/Loss - Plaquenil and losing eyelashesSigns of plaquenil overdosePlaquenil help sex driveChloroquine autophagy inhibition Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells. Plaquenil oral Reviews and User Ratings Effectiveness, Ease.. Long-Term Side Effects of Plaquenil for Rheumatoid.. Plaquenil Side Effects - GoodRx. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Side effects The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs.