Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Financial assistance for hydroxychloroquine Plaquenil and dizziness Nurse teaching to a patient taking hydroxychloroquine Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. This medicine is not effective against all strains of malaria. Malaria is common in areas such as Africa, South America, and Southern Asia. Drugs for rheumatoid arthritis starting with hydroxychloroquine Hydroxychloroquine Uses, Dosage & Side Effects -, Treatments for Rheumatoid Arthritis Afraid to try plaquenilPlaquenil for adenomyosis What Conditions Does This Treat? Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. RA and Hydroxychloroquine How Effective is it for Rheumatoid.. Taking Plaquenil for Rheumatoid Arthritis. Plaquenil User Reviews for Rheumatoid Arthritis at. Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. Most patients with Rheumatoid Arthritis RA will, at some point, use over-the-counter medications to control pain -- most commonly, acetaminophen Tylenol. Other OTC medications which can help with RA pain and inflammation include aspirin and non-prescription versions of ibuprofen Advil, Motrin or naproxen Aleve. DMARDs have greatly improved the quality of life for many people with rheumatoid arthritis. These RA drugs are often used along with NSAIDs or glucocorticoids; however, with this type of medication, you may not need other anti-inflammatories or analgesics. Because DMARDs target the immune system.