Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Aralens.ir Plaquenil and reduced renal function Why do some supplements call generic hydroxychloroquine brand name Chloroquine and hydroxychloroquine both belong to the quinolone family and share similar clinical indications and side effects, including retinal toxicity. Chloroquine-induced retinal toxicity was first described in 1959 and the retinal toxic effects of hydroxychloroquine were later described in 1967 3, 4. Hydroxychloroquine retinopathy is thought to be infrequent but of increasing prevalence because patients use the drug for many years or have undue exposure from overdosage or renal failure. 1 Screening in previous decades was primarily by subjective functional measures, such as the central visual field. Marmor MF, Kellner U, Lai TYY, Lyons JS, Mieler WF. Revised recommendations on screening for chloroquine and hydroxychloroquine retinopathy Ophthalmology 2011; 118 415-422. Hart WM, Burde RM, Johnston GP, Drews RC. Static perimetry in chloroquine retinopathy perifoveal patterns of visual field depression. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Plaquenil retinopathy visual fields AMERICAN COLLEGE OF RHEUMATOLOGY, Disparity between Visual Fields and Optical Coherence. Does hydroxychloroquine thin the bloodPlaquenil causing worse asthma problemsDry skin and plaquenilChloroquine and paludrine in pregnancy Nov 01, 2015 Advanced cases may demonstrate widespread retinal pigment epithelium atrophy, with a reduced visual field and decreased night vision. 3. Visual field. Parafoveal sensitivity loss is an early sign that may precede fundus changes. A computerized white-on-white 10-2 visual field test enables good resolution to test for macular sensitivity. Retinal Physician - Hydroxychloroquine Maculopathy An Update.. Humphrey Visual Field Findings in Hydroxychloroquine Toxicity. Humphrey visual field findings in hydroxychloroquine toxicity. Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity, including the cornea, ciliary body, and retina. Chloroquine can cause cataract; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Bull’s Eye Retinopathy. • 10-2 central threshold automated visual fields with a white target • Subtle, repeatable visual field defectsshould be taken seriously and are an indication to do objective testing. Chloroquine and Hydroxychloroquine Retinopathy. Opthalmology. 2011;18 2 415-422. Plaquenil therapy and eye exams. De__0__0. I was told from the start by my rheumatologist I would have to have eye exams including visual field exams every six months due to the plaquenil therapy. My first two exams did include these tests. But my next six month appointment is coming up, and they told me I didn't need the visual field test.