It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. What is the best time to take plaquenil Supplement chloroquine with antifungal medications as prescribed One hundred and forty-two patients with 'definite' or 'classical' rheumatoid arthritis RA were studied for the frequency and possible prognostic significance of HLA DR4. Of these, 122 were seropositive, while 20 were negative for rheumatoid factor RF in serum. User Reviews for Hydroxychloroquine to treat Rheumatoid Arthritis. Also known as Plaquenil, Quineprox. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Overview; Side Effects; Dosage Dec 29, 2009 Hydroxychloroquine Plaquenil, an antimalarial drug used in lupus and rheumatoid arthritis, may be helpful in some patients with SjÃ¶gren's syndrome by reducing joint pain and rash. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hla-dr4 rheumatoid arthritis and hydroxychloroquine Hydroxychloroquine User Reviews for Rheumatoid Arthritis., Hydroxychloroquine User Reviews for Rheumatoid Arthritis at. High triglycerides and plaquenilIs hydroxychloroquine antiviral Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. When the first biologic DMARD received FDA-approval in 1998, and as other biologics followed in subsequent years, it appeared as though Plaquenil would become less prescribed. Taking Plaquenil for Rheumatoid Arthritis. Rheumatoid Arthritis and Sjögren’s Syndrome - Eye Health.. Hydroxychloroquine Reviews Everyday Health. Feb 19, 2020 Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Inherited susceptibility to rheumatoid arthritis RA is associated with the DRB1 genes encoding the human leukocyte antigen HLA-DR4 and HLA-DR1 molecules. Transgenic mice expressing these major histocompatibility complex MHC class II molecules. Definition The major histocompatibility complex locus designated HLA-DR4 was first associated with RA in studies reported by Stastny in 1978. Using the technique of mixed lymphocyte culture, patients with RA were found to be more alike than were normal individuals, suggesting the presence of a shared cell-associated antigen.