Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Does plaquenil affect blood pressure Plaquenil american college of rheumatology Ocular migraine plaquenil I have SLE, Sjogren's APS, Hemolytic Anemia, Heart disease and now the neuropathy in my right leg. It takes a really long time for the Plaquenil to kick in. It takes a really long time for the Plaquenil to kick in. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Frequency not reported Skeletal muscle myopathy or neuromyopathy leading to progressive weakness and atrophy of proximal muscle groups, depression of tendon reflexes and abnormal nerve conduction studies. Myopathy may be reversible after therapy discontinuation, but recovery may take many months. Nervous system Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Discontinuing plaquenil now have muscle spasms Hydroxychloroquine Sulfate Muscle Spasms Reports., Plaquenil Hydroxychloroquine - Side Effects, Dosage. Otis pregnancy plaquenilAralen dosageCan plaquenil cause hypoglycemiaDoes plaquenil cause tinnitus The medications with a high risk of causing leg cramps are certain asthma medications and diuretics, but countless others can have muscle twitches and spasms as even a low-risk side effect. That said, no one should cease taking a medication without first consulting a doctor. Leading Causes Of Muscle Twitches And Spasms - HealthPrep. Plaquenil Side Effects Common, Severe, Long Term -. Rx Side Effects New Plaquenil Guidelines and More.. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about. Myoclonus describes a symptom and not a diagnosis of a disease. It refers to sudden, involuntary jerking of a muscle or group of muscles. Myoclonic twitches or jerks usually are caused by sudden muscle contractions, called positive myoclonus, or by muscle relaxation, called negative myoclonus. Clinical trial reports, you name it. I also have muscle spasms, mostly when I am sitting in bed or lyind down. For a while I was suffering with "charlie horses". The doctor tested my aldolase level and it was high, but now it's back to normal but I still have treamors and spasms. They are a nuisance. Hope things are good with you right now.